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АНАЛИЗ АЛЛЕЛЬНОГО ДИСБАЛАНСА ПРИ ГЛИОБЛАСТОМЕ: НОВЫЕ ХРОМОСОМНЫЕ УЧАСТКИ ПОТЕРИ ГЕТЕРОЗИГОТНОСТИ И НОВЫЕ ГЕНЫ-КАНДИДАТЫ

Published in Медицинская генетика • Dec 22, 2015
Authors:
Е. А. Алексеева
,
А. С. Танас
,
Е. В. Прозоренко

Abstract

By means of microsatellite analysis we have evaluated allelic status of eleven chromosome loci for which allelic imbalance (AI) had never been described in glioblastoma. Two of the eleven loci, 18q11.2 and 21q21.1, revealed no allelic imbalance in 108 glioblastoma samples. However, AI was identified...

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