Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Tie, J.; Wang, Yuxuan; Tomasetti, C.; Li, Lu; Springer, S.; Kinde, I.; Silliman, Natalie; Tacey, M.; Wong, H.; Christie, M.; Kosmider, S.; J Skinner, Iain; Wong, R.; Steel, M.; Tran, B.; Desai, J.; Jones, I.; Haydon, A.; Hayes, T.; Price, T.; Strausberg, R.; Diaz, L.; Papadopoulos, N.; Kinzler, K.; Vogelstein, B.; Gibbs, P.

doi:10.1126/scitranslmed.aaf6219

Public

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Shared by NobleBlocks on Jul 6, 2016 • 12:00 AM UTC

Authors:

J. Tie

Yuxuan Wang

C. Tomasetti

Abstract

Detection of circulating tumor DNA in patients with resected stage II colon cancer provides evidence of residual disease. Footprints of persistent cancer Stage II colon cancer, which has spread through the wall of the colon but has not metastasized to the lymph nodes, can present a therapeutic dilem...

Subject

Medicine

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