Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).

Z, Nikitaki; V, Nikolov; IV, Mavragani; E, Mladenov; A, Mangelis; DA, Laskaratou; GI, Fragkoulis; CE, Hellweg; OA, Martin; D, Emfietzoglou; VI, Hatzi; GI, Terzoudi; G, Iliakis; AG, Georgakilas

doi:10.1080/10715762.2016.1232484

Public

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).

Shared by NobleBlocks on Oct 25, 2016 • 12:00 AM UTC

Authors:

Nikitaki Z

Nikolov V

Mavragani IV

Abstract

Detrimental effects of ionizing radiation (IR) are correlated to the varying efficiency of IR to induce complex DNA damage. A double strand break (DSB) can be considered the simpler form of complex DNA damage. These types of damage can consist of DSBs, single strand breaks (SSBs) and/or non-DSB lesi...

Subject

DNA repair

Monte Carlo simulation

Complex Dna Damage

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