Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.

MD, Kessler; L, Yerges-Armstrong; MA, Taub; AC, Shetty; K, Maloney; LJB, Jeng; I, Ruczinski; AM, Levin; LK, Williams; TH, Beaty; RA, Mathias; KC, Barnes; TD, O'Connor

doi:10.1038/ncomms12521

Public

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.

Shared by NobleBlocks on Oct 11, 2016 • 12:00 AM UTC

Authors:

Kessler MD

Yerges-Armstrong L

Taub MA

Abstract

To characterize the extent and impact of ancestry-related biases in precision genomic medicine, we use 642 whole-genome sequences from the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) project to evaluate typical filters and databases. We find significant correlatio...

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