A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.

B, Witkowski; V, Duru; N, Khim; LS, Ross; B, Saintpierre; J, Beghain; S, Chy; S, Kim; S, Ke; N, Kloeung; R, Eam; C, Khean; M, Ken; K, Loch; A, Bouillon; A, Domergue; L, Ma; C, Bouchier; R, Leang; R, Huy; G, Nuel; JC, Barale; E, Legrand; P, Ringwald; DA, Fidock; O, Mercereau-Puijalon; F, Ariey; D, Ménard

doi:10.1016/s1473-3099(16)30415-7

Public

A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study.

Shared by NobleBlocks on Nov 3, 2016 • 12:00 AM UTC

Authors:

Witkowski B

Duru V

Khim N

Abstract

<h4>Background</h4>Western Cambodia is the epicentre of Plasmodium falciparum multidrug resistance and is facing high rates of dihydroartemisinin-piperaquine treatment failures. Genetic tools to detect the multidrug-resistant parasites are needed. Artemisinin resistance can be tracked using the K13 ...

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