Bacterial ghosts as adjuvants in syngeneic tumour cell lysate-based anticancer vaccination in a murine lung carcinoma model.

JA, Kraśko; K, Žilionytė; A, Darinskas; M, Strioga; S, Rjabceva; I, Zalutsky; M, Derevyanko; V, Kulchitsky; W, Lubitz; P, Kudela; E, Miseikyte-Kaubriene; O, Karaman; H, Didenko; H, Potebnya; V, Chekhun; V, Pašukonienė

doi:10.3892/or.2016.5252

Public

Bacterial ghosts as adjuvants in syngeneic tumour cell lysate-based anticancer vaccination in a murine lung carcinoma model.

Shared by NobleBlocks on Nov 16, 2016 • 12:00 AM UTC

Authors:

Kraśko JA

Žilionytė K

Darinskas A

Abstract

Instead of relying on external anticancer factors for treatment, immunotherapy utilizes the host's own immune system and directs it against given tumour antigens. This study demonstrated that it is possible to overcome the documented immunosuppressive properties of tumour cell lysate by supplementin...

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