Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.

ME, Melisko; ME, Goldman; J, Hwang; Luca A, De; S, Fang; LJ, Esserman; AJ, Chien; JW, Park; HS, Rugo

doi:10.1001/jamaoncol.2016.3904

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Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.

Shared by NobleBlocks on Mar 1, 2017 • 12:00 AM UTC

Authors:

Melisko ME

Goldman ME

Hwang J

Abstract

<h4>Importance</h4>Aromatase inhibitors (AI) are associated with significant urogenital atrophy, affecting quality of life and drug compliance.<h4>Objective</h4>To evaluate safety of intravaginal testosterone cream (IVT) or an estradiol-releasing vaginal ring (7.5 μg/d) in patients with early-stage ...

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