In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways.

Y, Chao; L, Li; D, Girodat; KU, Förstner; N, Said; C, Corcoran; M, Śmiga; K, Papenfort; R, Reinhardt; HJ, Wieden; BF, Luisi; J, Vogel

doi:10.1016/j.molcel.2016.11.002

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In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways.

Published in Molecular cell • Jan 1, 2017

Authors:

Chao Y

Li L

Girodat D

Abstract

Understanding RNA processing and turnover requires knowledge of cleavages by major endoribonucleases within a living cell. We have employed TIER-seq (transiently inactivating an endoribonuclease followed by RNA-seq) to profile cleavage products of the essential endoribonuclease RNase E in Salmonella...

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Open Access

Subject

non-coding RNA

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