Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures

A.B. van den Bogaard, Veerle; D.P. Ta, Bastiaan; van der Schaaf, Arjen; B. Bouma, Angelique; M.H. Middag, Astrid; J. Bantema-Joppe, Enja; V. van Dijk, Lisanne; B.J. van Dijk-Peters, Femke; A.W. Marteijn, Laurens; H. de Bock, Gertruida; G.M. Burgerhof, Johannes; A. Gietema, Jourik; A. Langendijk, Johannes; H. Maduro, John; P.G Crijns, Anne

doi:10.1200/jco.2016.69.8480

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Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures

Shared by NobleBlocks on Apr 10, 2017 • 12:00 AM UTC

Authors:

Veerle A.B. van den Bogaard

Bastiaan D.P. Ta

Arjen van der Schaaf

Abstract

Purpose A relationship between mean heart dose (MHD) and acute coronary event (ACE) rate was reported in a study of patients with breast cancer (BC). The main objective of our cohort study was to validate this relationship and investigate if other dose-distribution parameters are better predictors f...

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