SRSF2 Regulates Alternative Splicing to Drive Hepatocellular Carcinoma Development.

C, Luo; Y, Cheng; Y, Liu; L, Chen; L, Liu; N, Wei; Z, Xie; W, Wu; Y, Feng

doi:10.1158/0008-5472.can-16-1919

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SRSF2 Regulates Alternative Splicing to Drive Hepatocellular Carcinoma Development.

Shared by NobleBlocks on Jan 12, 2017 • 12:00 AM UTC

Authors:

Luo C

Cheng Y

Liu Y

Abstract

Aberrant RNA splicing is recognized to contribute to cancer pathogenesis, but the underlying mechanisms remain mainly obscure. Here, we report that the splicing factor SRSF2 is upregulated frequently in human hepatocellular carcinoma (HCC), where this event is associated with poor prognosis in patie...

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