A Novel Human <i>CAMK2A</i> Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

Characterizing the functional impact of novel mutations linked to autism spectrum disorder (ASD) provides a deeper mechanistic understanding of the underlying pathophysiological mechanisms. Here we show that a <i>de novo</i> Glu183 to Val (E183V) mutation in the CaMKIIα catalytic domain, identified ... View More