m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.

Q, Cui; H, Shi; P, Ye; L, Li; Q, Qu; G, Sun; G, Sun; Z, Lu; Y, Huang; CG, Yang; AD, Riggs; C, He; Y, Shi

doi:10.1016/j.celrep.2017.02.059

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m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.

Shared by NobleBlocks on Mar 1, 2017 • 12:00 AM UTC

Authors:

Cui Q

Shi H

Ye P

Abstract

RNA modifications play critical roles in important biological processes. However, the functions of N6-methyladenosine (m6A) mRNA modification in cancer biology and cancer stem cells remain largely unknown. Here, we show that m6A mRNA modification is critical for glio...

Subject

Mettl3

Glioblastoma Stem Cells

Mettl14

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