Treatment of Endometriosis‐Associated Pain with Elagolix, an Oral GnRH Antagonist

Hs, Tay; Lc, Giudice; Ba, Lessey; Ms, Abrao; J, Kotarski; Df, Archer; Mp, Diamond; E, S.; Np, Johnson; Nb, Watts; Jc, Gallagher; Ja, Simon; Br, Carr; Wp, Dmowski; N, Leyland; Jp, Rowan; Wr, Duan; J, N.; B, Schwefel; Jw, Thomas; Ri, Jain; K, Chwalisz

doi:10.1056/NEJMoa1700089

Public

Treatment of Endometriosis‐Associated Pain with Elagolix, an Oral GnRH Antagonist

Shared by NobleBlocks on May 19, 2017 • 12:00 AM UTC

Authors:

Tay Hs

Giudice Lc

Lessey Ba

Abstract

Background Endometriosis is a chronic, estrogen‐dependent condition that causes dysmenorrhea and pelvic pain. Elagolix, an oral, nonpeptide, gonadotropin‐releasing hormone (GnRH) antagonist, produced partial to nearly full estrogen suppression in previous studies. Methods We performed two similar, d...

Subject

Medicine

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