Cancer risk and survival in <i>path_MMR</i> carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database.

P, Møller; TT, Seppälä; I, Bernstein; E, Holinski-Feder; P, Sala; Evans D, Gareth; A, Lindblom; F, Macrae; I, Blanco; RH, Sijmons; J, Jeffries; HFA, Vasen; J, Burn; S, Nakken; E, Hovig; EA, Rødland; K, Tharmaratnam; Vos Tot Nederveen Cappel WH, de; J, Hill; JT, Wijnen; MA, Jenkins; K, Green; F, Lalloo; L, Sunde; M, Mints; L, Bertario; M, Pineda; M, Navarro; M, Morak; L, Renkonen-Sinisalo; MD, Valentin; IM, Frayling; JP, Plazzer; K, Pylvanainen; M, Genuardi; JP, Mecklin; G, Moeslein; JR, Sampson; G, Capella

doi:10.1136/gutjnl-2017-314057

Public

Cancer risk and survival in <i>path_MMR</i> carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database.

Shared by NobleBlocks on Jul 28, 2017 • 12:00 AM UTC

Authors:

Møller P

Seppälä TT

Bernstein I

Abstract

<h4>Background</h4>Most patients with <i>path_MMR</i> gene variants (Lynch syndrome (LS)) now survive both their first and subsequent cancers, resulting in a growing number of older patients with LS for whom limited information exists with respect to cancer risk and survival.<h4>Objective and design...

Subject

Clinical Trials

Cancer Prevention

Colorectal Cancer Screening

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