Tumor Necrosis Factor‐Alpha: Role in Development of Insulin Resistance and Pathogenesis of Type 2 Diabetes Mellitus

Akash, M.; Rehman, K.; Liaqat, Aamira

doi:10.1002/jcb.26174

Public

Tumor Necrosis Factor-Alpha: Role in Development of Insulin Resistance and Pathogenesis of Type 2 Diabetes Mellitus.

Published in Journal of cellular biochemistry • Jun 22, 2017

Authors:

Akash MSH

Rehman K

Liaqat A

Abstract

Pathogenesis of type 2 diabetes mellitus (T2DM) and development of insulin resistance are characterized by multi-stimuli factors notably glucolipotoxicity, generation of reactive oxygen species (ROS), epigenetic factors, activation of various transcriptional mediated pathways along with the augmente...

Subject

Insulin resistance

Type 2 diabetes mellitus

TNF-α

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