Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Nolte, I.; Muñoz, M.; Tragante, V.; Amare, A.; Amare, A.; Jansen, R.; Vaez, A.; Vaez, A.; von der Heyde, Benedikt; Avery, C.; Bis, J.; Dierckx, B.; Dongen, J.; Gogarten, S.; Goyette, P.; Hernesniemi, J.; Huikari, V.; Hwang, Shih-Jen; Jaju, D.; F. Kerr, Kathleen; Kluttig, A.; Krijthe, B.; Kumar, J.; W. Laan, S.; Lyytikäinen, L.; Maihofer, A.; Minassian, A.; J. Most, P.; Müller-Nurasyid, M.; Nivard, M.; Salvi, E.; Stewart, J.; Thayer, J.; Verweij, N.; Wong, A.; Zabaneh, D.; Zabaneh, D.; Zafarmand, M.; Abdellaoui, A.; Albarwani, S.; Albert, C.; Alonso, Á.; N. Ashar, Foram; Auvinen, J.; Axelsson, T.; Baker, D.; D. Bakker, P.; Barcella, M.; Bayoumi, R.; J. Bieringa, Rob; Boomsma, D.; Boucher, G.; Britton, A.; E. Christophersen, I.; E. Christophersen, I.; E. Christophersen, I.; Dietrich, A.; Ehret, G.; Ehret, G.; Ellinor, P.; Ellinor, P.; Eskola, M.; Felix, J.; Floras, J.; Franco, O.; Friberg, P.; Gademan, M.; Geyer, M.; Giedraitis, V.; Hartman, C.; Hemerich, Daiane; Hemerich, Daiane; Hofman, A.; Hottenga, J.; Huikuri, H.; Hutri-Kähönen, N.; Jouven, X.; Junttila, J.; Juonala, M.; Kiviniemi, A.; Kors, J.; Kumari, Meena; Kumari, Meena; Kuznetsova, T.; Laurie, C.; Lefrandt, J.; Li, Yong; Li, Yun; Liao, Duanping; Limacher, M.; J. Lin, Henry; Lindgren, C.; Lubitz, S.; Lubitz, S.; Mahajan, A.; Mcknight, B.; Mcknight, B.; M. Schwabedissen, H.; Milaneschi, Y.; Mononen, N.; P. Morris, A.; P. Morris, A.; Nalls, M.; Navis, G.; Neijts, M.; Nikus, K.; North, K.; O'Connor, D.; Ormel, J.; Perz, S.; Peters, A.; M. Psaty, Bruce; M. Psaty, Bruce; Raitakari, O.; Risbrough, V.; F. Sinner, Moritz; Siscovick, D.; Smit, J.; L. Smith, N.; L. Smith, N.; Soliman, E.; Sotoodehnia, N.; Staessen, J.; Stein, P.; Stilp, A.; Stolarz-Skrzypek, K.; Strauch, K.; Sundström, J.; A. Swenne, C.; Syvänen, A.; Tardif, J.; Taylor, K.; Teumer, A.; Thornton, T.; E. Tinker, Lesley; Uitterlinden, A.; V. Setten, J.; Voss, A.; Waldenberger, M.; C. Wilhelmsen, Kirk; C. Wilhelmsen, Kirk; Willemsen, G.; Wong, Q.; Zhang, Zhu-ming; Zonderman, A.; Cusi, D.; Evans, M.; Greiser, H.; Harst, P.; Hassan, Mohammad; Ingelsson, E.; Ingelsson, E.; Järvelin, M.; Järvelin, M.; Kääb, S.; Kähönen, M.; Kivimäki, M.; Kooperberg, C.; Kuh, D.; Lehtimäki, T.; Lind, L.; Nievergelt, C.; J. O'Donnell, Christopher; Oldehinkel, A.; Penninx, B.; P. Reiner, Alexander; P. Reiner, Alexander; Riese, H.; V. Roon, A.; Rioux, J.; Rotter, J.; Sofer, T.; Stricker, B.; Tiemeier, H.; Vrijkotte, T.; Asselbergs, F.; Asselbergs, F.; Brundel, B.; Heckbert, S.; Whitsel, E.; Hoed, M.; Snieder, H.; D. Geus, E.

doi:10.1038/ncomms15805

Public

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Shared by NobleBlocks on Jun 14, 2017 • 12:00 AM UTC

Authors:

I. Nolte

M. Muñoz

V. Tragante

Abstract

Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-w...

Subject

Biology

Medicine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!