Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

SH, Witt; F, Streit; M, Jungkunz; J, Frank; S, Awasthi; CS, Reinbold; J, Treutlein; F, Degenhardt; AJ, Forstner; S, Heilmann-Heimbach; L, Dietl; CE, Schwarze; D, Schendel; J, Strohmaier; A, Abdellaoui; R, Adolfsson; TM, Air; H, Akil; M, Alda; N, Alliey-Rodriguez; OA, Andreassen; G, Babadjanova; NJ, Bass; M, Bauer; BT, Baune; F, Bellivier; S, Bergen; A, Bethell; JM, Biernacka; DHR, Blackwood; MP, Boks; DI, Boomsma; AD, Børglum; M, Borrmann-Hassenbach; P, Brennan; M, Budde; HN, Buttenschøn; EM, Byrne; P, Cervantes; TK, Clarke; N, Craddock; C, Cruceanu; D, Curtis; PM, Czerski; U, Dannlowski; T, Davis; Geus EJC, de; Florio A, Di; S, Djurovic; E, Domenici; HJ, Edenberg; B, Etain; SB, Fischer; L, Forty; C, Fraser; MA, Frye; JM, Fullerton; K, Gade; ES, Gershon; I, Giegling; SD, Gordon; K, Gordon-Smith; HJ, Grabe; EK, Green; TA, Greenwood; M, Grigoroiu-Serbanescu; J, Guzman-Parra; LS, Hall; M, Hamshere; J, Hauser; M, Hautzinger; U, Heilbronner; S, Herms; S, Hitturlingappa; P, Hoffmann; P, Holmans; JJ, Hottenga; S, Jamain; I, Jones; LA, Jones; A, Juréus; RS, Kahn; J, Kammerer-Ciernioch; G, Kirov; S, Kittel-Schneider; S, Kloiber; SV, Knott; M, Kogevinas; M, Landén; M, Leber; M, Leboyer; QS, Li; J, Lissowska; S, Lucae; NG, Martin; F, Mayoral-Cleries; SL, McElroy; AM, McIntosh; JD, McKay; A, McQuillin; SE, Medland; CM, Middeldorp; Y, Milaneschi; PB, Mitchell; GW, Montgomery; G, Morken; O, Mors; TW, Mühleisen; B, Müller-Myhsok; RM, Myers; CM, Nievergelt; JI, Nurnberger; MC, O'Donovan; LMO, Loohuis; R, Ophoff; L, Oruc; MJ, Owen; SA, Paciga; BWJH, Penninx; A, Perry; A, Pfennig; JB, Potash; M, Preisig; A, Reif; F, Rivas; GA, Rouleau; PR, Schofield; TG, Schulze; M, Schwarz; L, Scott; GCB, Sinnamon; EA, Stahl; J, Strauss; G, Turecki; der Auwera S, Van; H, Vedder; JB, Vincent; G, Willemsen; CC, Witt; NR, Wray; HS, Xi; A, Tadic; N, Dahmen; BH, Schott; S, Cichon; MM, Nöthen; S, Ripke; A, Mobascher; D, Rujescu; K, Lieb; S, Roepke; C, Schmahl; M, Bohus; M, Rietschel

doi:10.1038/tp.2017.115

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Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Shared by NobleBlocks on Jun 20, 2017 • 12:00 AM UTC

Authors:

Witt SH

Streit F

Jungkunz M

Abstract

Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder (BIP). Up to 20% of BIP patients show comorbidity with BOR. This report describe...

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