Epigenome-wide Association of PTSD from Heterogeneous Cohorts with a Common Multi-Site Analysis Pipeline

Ratanatharathorn, A.; Boks, M.; Maihofer, A.; Aiello, A.; Amstadter, A.; Ashley-Koch, A.; Baker, D.; Beckham, J.; Bromet, E.; F. Dennis, Michelle; Garrett, M.; Geuze, E.; Guffanti, G.; Hauser, M.; Kilaru, V.; Kimbrel, N.; Koenen, K.; Kuan, Pei-Fen; Logue, M.; Luft, B.; W. Miller, Mark; M. Mitchell, Colter; Nugent, N.; Ressler, K.; Rutten, B.; Stein, M.; Vermetten, E.; Vinkers, C.; Youssef, N.; Uddin, M.; Nievergelt, C.; K. Smith, Alicia

doi:10.1002/ajmg.b.32568

Public

Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.

Shared by NobleBlocks on Jul 10, 2017 • 12:00 AM UTC

Authors:

Ratanatharathorn A

Boks MP

Maihofer AX

Abstract

Compelling evidence suggests that epigenetic mechanisms such as DNA methylation play a role in stress regulation and in the etiologic basis of stress related disorders such as Post traumatic Stress Disorder (PTSD). Here we describe the purpose and methods of an international consortium that was deve...

Subject

Stress

Trauma

Meta-analysis

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