FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer.

S, Yang; Y, Liu; MY, Li; CSH, Ng; SL, Yang; S, Wang; C, Zou; Y, Dong; J, Du; X, Long; LZ, Liu; IYP, Wan; T, Mok; MJ, Underwood; GG, Chen

doi:10.1186/s12943-017-0700-1

Public

FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer.

Shared by NobleBlocks on Jul 17, 2017 • 12:00 AM UTC

Authors:

Yang S

Liu Y

Li MY

Abstract

<h4>Background</h4>The role of cancer cell FOXP3 in tumorigenesis is conflicting. We aimed to study FOXP3 expression and regulation, function and clinical implication in human non-small cell lung cancer (NSCLC).<h4>Methods</h4>One hundred and six patients with histologically-confirmed NSCLC who unde...

Subject

Wnt

NSCLC

Emt

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!