Suzuki-Miyaura cross-coupling of amides and esters at room temperature: correlation with barriers to rotation around C-N and C-O bonds.

P, Lei; G, Meng; S, Shi; Y, Ling; J, An; R, Szostak; M, Szostak

doi:10.1039/c7sc02692g

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Suzuki-Miyaura cross-coupling of amides and esters at room temperature: correlation with barriers to rotation around C-N and C-O bonds.

Published in Chemical science • Aug 1, 2017

Authors:

Lei P

Meng G

Shi S

Abstract

The Suzuki-Miyaura cross-coupling has been widely recognized as one of the most important methods for the construction of C-C bonds. However, in contrast to traditional aryl halide or pseudohalide electrophiles, coupling reactions with unactivated C-N and C-O electrophiles have proven significantly ...

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