Mir-21 Promotes Cardiac Fibrosis After Myocardial Infarction Via Targeting Smad7.

J, Yuan; H, Chen; D, Ge; Y, Xu; H, Xu; Y, Yang; M, Gu; Y, Zhou; J, Zhu; T, Ge; Q, Chen; Y, Gao; Y, Wang; X, Li; Y, Zhao

doi:10.1159/000479995

Public

Mir-21 Promotes Cardiac Fibrosis After Myocardial Infarction Via Targeting Smad7.

Shared by NobleBlocks on Aug 16, 2017 • 12:00 AM UTC

Authors:

Yuan J

Chen H

Ge D

Abstract

<h4>Background/aims</h4>Cardiac fibrosis after myocardial infarction (MI) has been identified as an important factor in the deterioration of heart function. Previous studies have demonstrated that miR-21 plays an important role in various pathophysiological processes in the heart. However, the role ...

Subject

Myocardial infarction

Smad7

TGF-β1

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