Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing

Shibuya, Yusuke; Tokunaga, Hideki; Saito, Sakae; Shimokawa, Kazurou; Katsuoka, Fumiki; Bin, Li; Kojima, Kaname; Nagasaki, Masao; Yamamoto, Masayuki; Yaegashi, Nobuo; Yasuda, Jun

doi:10.1002/gcc.22507

Public

Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing

Shared by NobleBlocks on Oct 28, 2017 • 12:00 AM UTC

Authors:

Yusuke Shibuya

Hideki Tokunaga

Sakae Saito

Abstract

Abstract Ovarian clear cell carcinoma (OCCC) is the most refractory subtype of ovarian cancer and more prevalent in Japanese than Caucasians (25% and 5% of all ovarian cancer, respectively). The aim of this study is to discover the genomic alterations that may cause OCCC and effective molecular targ...

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