LncRNA-XIST interacts with <i>miR-29c</i> to modulate the chemoresistance of glioma cell to TMZ through DNA mismatch repair pathway.

P, Du; H, Zhao; R, Peng; Q, Liu; J, Yuan; G, Peng; Y, Liao

doi:10.1042/bsr20170696

Public

LncRNA-XIST interacts with <i>miR-29c</i> to modulate the chemoresistance of glioma cell to TMZ through DNA mismatch repair pathway.

Shared by NobleBlocks on Sep 7, 2017 • 12:00 AM UTC

Authors:

Du P

Zhao H

Peng R

Abstract

Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy. However, growing resistance to TMZ remains a major challenge for clinicians. Recent evidence emphasizes the key regulatory roles of non-coding RNAs (lncRNAs and miRNAs) in tumor biology, including the chemoresistan...

Subject

Glioma

Chemoresistance

Temozolomide (Tmz)

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