Modelling the Survival Outcomes of Immuno-Oncology Drugs in Economic Evaluations: A Systematic Approach to Data Analysis and Extrapolation.

E, Gibson; I, Koblbauer; N, Begum; G, Dranitsaris; D, Liew; P, McEwan; Monfared AA, Tahami; Y, Yuan; A, Juarez-Garcia; D, Tyas; M, Lees

doi:10.1007/s40273-017-0558-5

Public

Modelling the Survival Outcomes of Immuno-Oncology Drugs in Economic Evaluations: A Systematic Approach to Data Analysis and Extrapolation.

Shared by NobleBlocks on Dec 1, 2017 • 12:00 AM UTC

Authors:

Gibson E

Koblbauer I

Begum N

Abstract

<h4>Background</h4>New immuno-oncology (I-O) therapies that harness the immune system to fight cancer call for a re-examination of the traditional parametric techniques used to model survival from clinical trial data. More flexible approaches are needed to capture the characteristic I-O pattern of d...

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