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Гломерулярная гипертензия: молекулярные механизмы повреждения подоцитов и мезангиальных клеток

Published in Nephrology (Saint-Petersburg) • Jul 1, 2016
NobleIDNI3P86W69R90S40
Authors:
Олег Борисович Кузьмин
,
Владислав Викторович Жежа
,
Виталий Васильевич Белянин

Abstract

The review presents data on the molecular mechanisms underlying podocytes and mesangial cells damage in glomerular hypertension. Mechanical stress in these cells activates the local RAS and increases the secretion of Ang II which in autocrine and paracrine manner stimulates AT1-receptors and trigger...

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