Reactive oxygen species scavengers ameliorate mechanical allodynia in a rat model of cancer-induced bone pain.

YQ, Zhou; DQ, Liu; SP, Chen; J, Sun; XR, Zhou; H, Rittner; W, Mei; YK, Tian; HX, Zhang; F, Chen; DW, Ye

doi:10.1016/j.redox.2017.10.011

Public

Reactive oxygen species scavengers ameliorate mechanical allodynia in a rat model of cancer-induced bone pain.

Shared by NobleBlocks on Oct 16, 2017 • 12:00 AM UTC

Authors:

Zhou YQ

Liu DQ

Chen SP

Abstract

Cancer-induced bone pain (CIBP) is a frequent complication in patients suffering from bone metastases. Previous studies have demonstrated a pivotal role of reactive oxygen species (ROS) in inflammatory and neuropathic pain, and ROS scavengers exhibited potent antinociceptive effect. However, the rol...

Subject

Reactive oxygen species

Tempol

Cancer-induced Bone Pain

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