Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation

Fiorito, Giovanni; Polidoro, Silvia; Dugué, Pierre-Antoine; Kivimaki, Mika; Ponzi, Erica; Matullo, Giuseppe; Guarrera, Simonetta; B. Assumma, Manuela; Georgiadis, Panagiotis; A. Kyrtopoulos, Soterios; Krogh, Vittorio; Palli, Domenico; Panico, Salvatore; Sacerdote, Carlotta; Tumino, Rosario; Chadeau-Hyam, Marc; Stringhini, Silvia; Severi, Gianluca; M. Hodge, Allison; G. Giles, Graham; Marioni, Riccardo; Karlsson Linnér, Richard; M. O’Halloran, Aisling; A. Kenny, Rose; Layte, Richard; Baglietto, Laura; Robinson, Oliver; McCrory, Cathal; L. Milne, Roger; Vineis, Paolo

doi:10.1038/s41598-017-16391-5

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Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation

Shared by NobleBlocks on Nov 24, 2017 • 12:00 AM UTC

Authors:

Giovanni Fiorito

Silvia Polidoro

Pierre-Antoine Dugué

Abstract

Abstract Low socioeconomic status (SES) is associated with earlier onset of age-related chronic conditions and reduced life-expectancy, but the underlying biomolecular mechanisms remain unclear. Evidence of DNA-methylation differences by SES suggests a possible association of SES with epigenetic age...

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