Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

LJW, Bosch; Wit M, de; TV, Pham; VMH, Coupé; AC, Hiemstra; SR, Piersma; G, Oudgenoeg; GL, Scheffer; S, Mongera; Droste JT, Sive; FA, Oort; Turenhout ST, van; IB, Larbi; J, Louwagie; Criekinge W, van; der Hulst RWM, van; CJJ, Mulder; B, Carvalho; RJA, Fijneman; CR, Jimenez; GA, Meijer

doi:10.7326/m17-1068

Public

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

Shared by NobleBlocks on Nov 21, 2017 • 12:00 AM UTC

Authors:

Bosch LJW

de Wit M

Pham TV

Abstract

<h4>Background</h4>The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvasive colorectal cancer (CRC) screening, but its sensitivity leaves room for improvement.<h4>Objective</h4>To identify novel protein biomarkers in stool that outperform or complement hemoglobin i...

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