A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults.

L, Ostergaard; T, Vesikari; J, Absalon; J, Beeslaar; BJ, Ward; S, Senders; JJ, Eiden; KU, Jansen; AS, Anderson; LJ, York; TR, Jones; SL, Harris; R, O'Neill; D, Radley; R, Maansson; JL, Prégaldien; J, Ginis; NB, Staerke; JL, Perez

doi:10.1056/nejmoa1614474

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A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults.

Shared by NobleBlocks on Dec 1, 2017 • 12:00 AM UTC

Authors:

Ostergaard L

Vesikari T

Absalon J

Abstract

<h4>Background</h4>MenB-FHbp is a licensed meningococcal B vaccine targeting factor H-binding protein. Two phase 3 studies assessed the safety of the vaccine and its immunogenicity against diverse strains of group B meningococcus.<h4>Methods</h4>We randomly assigned 3596 adolescents (10 to 18 years ...

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