Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.

L, Laencina; V, Dubois; Moigne V, Le; A, Viljoen; L, Majlessi; J, Pritchard; A, Bernut; L, Piel; AL, Roux; JL, Gaillard; B, Lombard; D, Loew; EJ, Rubin; R, Brosch; L, Kremer; JL, Herrmann; F, Girard-Misguich

doi:10.1073/pnas.1713195115

Public

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.

Published in Proceedings of the National Academy of Sciences of the United States of America • Jan 17, 2018

Authors:

Laencina L

Dubois V

Le Moigne V

Abstract

Mycobacterium abscessus, a rapidly growing mycobacterium (RGM) and an opportunistic human pathogen, is responsible for a wide spectrum of clinical manifestations ranging from pulmonary to skin and soft tissue infections. This intracellular organism can resist the bactericidal defense mechanis...

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Open Access

Subject

Survival

M. Abscessus

Tviiss-esx4

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