The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2.

P, Neumann; N, Jaé; A, Knau; SF, Glaser; Y, Fouani; O, Rossbach; M, Krüger; D, John; A, Bindereif; P, Grote; RA, Boon; S, Dimmeler

doi:10.1038/s41467-017-02431-1

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The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2.

Shared by NobleBlocks on Jan 16, 2018 • 12:00 AM UTC

Authors:

Neumann P

Jaé N

Knau A

Abstract

Impaired or excessive growth of endothelial cells contributes to several diseases. However, the functional involvement of regulatory long non-coding RNAs in these processes is not well defined. Here, we show that the long non-coding antisense transcript of GATA6 (GATA6-AS) interacts with the epigene...

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