Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi.

Amino acid esters are a group of structurally diverse natural products with distinct activities. Some are synthesized through an inter-molecular esterification step catalysed by nonribosomal peptide synthetase (NRPS). In bacteria, the formation of the intra-molecular ester bond is usually catalysed ... View More