Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Wood, A.; Kaptoge, S.; Butterworth, A.; Willeit, Peter; Warnakula, S.; Bolton, T.; Paige, Ellie; S. Paul, Dirk; J Sweeting, Michael; Burgess, Stephen; Bell, S.; Astle, W.; Stevens, David; Koulman, A.; Selmer, R.; Verschuren, W.; Sato, S.; Njølstad, I.; Woodward, M.; Salomaa, V.; Nordestgaard, B.; Yeap, B.; Fletcher, A.; Melander, O.; H. Kuller, Lewis; Balkau, B.; Marmot, Michael; Koenig, Wolfgang; Casiglia, Edoardo; Cooper, Cyrus; Arndt, Volker; H. Franco, Oscar; Wennberg, Patrik; Gallacher, J.; G. de la Cámara, A.; Völzke, H.; Dahm, C.; Dale, C.; Bergmann, M.; Crespo, C.; T. van der Schouw, Y.; Kaaks, R.; A. Simons, Leon; Lagiou, P.; Schoufour, J.; Boer, J.; J. Key, T.; Rodríguez, B.; Moreno-Iribas, Conchi; W. Davidson, Karina; O. Taylor, James; Sacerdote, C.; Wallace, Robert; Quirós, J.; Tumino, R.; Blazer, D.; Linneberg, A.; Daimon, M.; Panico, S.; V. Howard, Barbara; Skeie, G.; E Strandberg, Timo; Weiderpass, E.; J. Nietert, Paul; Psaty, B.; Kromhout, D.; Salamanca-Fernández, E.; Kiechl, S.; Krumholz, H.; Grioni, S.; Palli, D.; M. Huerta, J.; Price, J.; Sundström, J.; Arrióla, L.; Arima, Hisatomi; Travis, R.; Panagiotakos, Demosthenes; Karakatsani, A.; Trichopoulou, A.; Kühn, T.; Grobbee, D.; Barrett-Connor, E.; V. van Schoor, N.; Boeing, H.; Overvad, K.; Kauhanen, J.; Wareham, N.; Langenberg, C.; Forouhi, N.; Wennberg, Maria; Després, J.; Cushman, Mary; Cooper, J.; Rodriguez, C.; Sakurai, Masaru; E. Shaw, Jonathan; Knuiman, M.; Voortman, T.; Meisinger, C.; Tjønneland, A.; Brenner, H.; Palmieri, Luigi; Dallongeville, J.; Brunner, E.; Assmann, Gerd; Trevisan, M.; Gillum, R.; Ford, Ian; Sattar, N.; Lazo, M.; G. Thompson, Simon; Ferrari, Pietro; A Leon, David; D. Smith, G.; Peto, R.; Jackson, Rod; Banks, E.; di Angelantonio, E.; N. Danesh, John; M Stephen Adam Peter Samantha Thomas Ellie Dirk S Wood Kaptoge Butterworth Willeit Warnakula Bolton, Angela; M. Wood, Angela; Kaptoge, S.; Butterworth, A.; Willeit, P.; Warnakula, S.; Bolton, T.; Paige, Ellie; S. Paul, Dirk; J Sweeting, Michael; Burgess, Stephen; Bell, S.; Astle, W.; Stevens, David; Koulman, Albert; Selmer, R.; Verschuren, M.; Sato, S.; Njølstad, I.; Woodward, Mark; Veikko, Salomaa; Nordestgaard, B.; Yeap, B.; Flecther, Astrid; Melander, Olle; H. Kuller, L.; Balkau, B.; Marmot, M.; Koenig, Wolfgang; Casiglia, Edoardo; Cooper, Cyrus; Arndt, V.; H. Franco, Oscar; Wennberg, P.; Gallacher, J.; Gómez de la Cámara, A.; Völzke, H.; Dahm, C.; Dale, C.; Bergmann, M.; Crespo, C.; T. van der Schouw, Y.; Kaaks, R.; Simons, L.; Lagiou, P.; Schoufour, J.; Boer, J.; J. Key, Timothy; Rodríguez, B.; Moreno-Iribas, Conchi; W. Davidson, Karina; O. Taylor, James; Sacerdote, C.; Wallace, Robert; Quirós, J.; Rimm, E.; Tumino, R.; G. Blazer III, Dan; Linneberg, A.; Daimon, M.; Panico, Salvatore; V. Howard, Barbara; Skeie, G.; Salomaa, V.; E Strandberg, Timo; Weiderpass, E.; J. Nietert, Paul; M. Psaty, Bruce; Kromhout, D.; Salamanca-Fernández, E.; Kiechl, S.; Krumholz, H.; Grioni, S.; Palli, D.; Huerta, J.; Price, J.; Sundström, Johan; Arrióla, L.; Arima, H.; Travis, R.; B Panagiotakos, Demosthenes; Karakatsani, A.; Trichopoulou, A.; Kühn, T.; Grobbee, D.; Barrett-Connor, E.; V. van Schoor, N.; Boeing, H.; Overvad, Kim; Kauhanen, J.; Wareham, N.; Langenberg, C.; Forouhi, N.; Wennberg, Maria; Despres, J.; Cushman, Mary; A. Cooper, Jackie; J. Rodríguez, C.; Sakurai, Masaru; Shaw, J.; Knuiman, M.; Voortman, T.; Meisinger, C.; Tjønneland, A.; Brenner, Hermann; Palmieri, Luigi; Dallongeville, J.; J Brunner, Eric; Assmann, Gerd; Trevisan, M.; F Gillumn, Richard; Ford, Ian; Sattar, Naveed; Lazo, Mariana; G. Thompson, Simon; Ferrari, Pietro; A. Leon, David; Davey Smith, G.; Peto, R.; Jackson, Rod; Banks, Emily; di Angelantonio, E.; N. Danesh, John

doi:10.1016/S0140-6736(18)30134-X

Public

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Shared by NobleBlocks on Apr 14, 2018 • 12:00 AM UTC

Authors:

A. Wood

S. Kaptoge

A. Butterworth

Abstract

Summary Background Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers wi...

Subject

Medicine

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