Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells.

C, Ordoñez; HP, Savage; M, Tarajia; R, Rivera; C, Weeks-Galindo; D, Sambrano; L, Riley; PL, Fernandez; N, Baumgarth; A, Goodridge

doi:10.1111/imm.12909

Public

Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells.

Shared by NobleBlocks on Feb 18, 2018 • 12:00 AM UTC

Authors:

Ordoñez C

Savage HP

Tarajia M

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. The cellular immune response to mycobacteria has been characterized extensively, but the antibody response remains underexplored. The present study aimed to examine whether host or bacterial phospholipids induce secretion of...

Subject

Autoantibodies

Activation

Bacterial

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