Altered expression of glutamate transporter‐1 and water channel protein aquaporin‐4 in human temporal cortex with Alzheimer's disease

Hoshi, A.; Tsunoda, A.; Yamamoto, T.; Tada, M.; Kakita, A.; Ugawa, Y.

doi:10.1111/nan.12475

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Altered expression of glutamate transporter‐1 and water channel protein aquaporin‐4 in human temporal cortex with Alzheimer's disease

Shared by NobleBlocks on Mar 4, 2018 • 12:00 AM UTC

Authors:

A. Hoshi

A. Tsunoda

T. Yamamoto

Abstract

Aims Glutamate neurotoxicity plays an important role in the pathogenesis of various neurodegenerative disorders. Many studies have demonstrated that glutamate transporter‐1 ( GLT ‐1), the dominant astrocytic glutamate transporter, is significantly reduced in the cerebral cortex of patients with Alzh...

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