Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis.

K, Kapodistria; EP, Tsilibary; E, Kotsopoulou; P, Moustardas; P, Kitsiou

doi:10.1111/jcmm.13259

Public

Liraglutide, a human glucagon-like peptide-1 analogue, stimulates AKT-dependent survival signalling and inhibits pancreatic β-cell apoptosis.

Shared by NobleBlocks on Mar 10, 2018 • 12:00 AM UTC

Authors:

Kapodistria K

Tsilibary EP

Kotsopoulou E

Abstract

Liraglutide, a human long-lasting GLP-1 analogue, is currently regarded as a powerful treatment option for type 2 diabetes. Apart from glucoregulatory and insulinotropic actions, liraglutide increases β-cell mass through stimulation of β-cell proliferation and islet neogenesis, as well as inhibition...

Subject

Apoptosis

Pancreatic Β-cells

Nephrin

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!