Genomic Profiling of Two Histologically Distinct Rare Urothelial Cancers in a Clinical Setting to Identify Potential Therapeutic Options for Treatment and Management of Disease.

AN, Hesse; W, Fabricius; CA, Thomas; R, Gaindh; R, Christman; P, Selvam; M, Prego; G, Lewis; J, Uvalic; D, Bergeron; S, Burns; B, Sisson; K, Kelly; J, Rueter; HV, Reddi

doi:10.1159/000487882

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Genomic Profiling of Two Histologically Distinct Rare Urothelial Cancers in a Clinical Setting to Identify Potential Therapeutic Options for Treatment and Management of Disease.

Shared by NobleBlocks on Jan 1, 2018 • 12:00 AM UTC

Authors:

Hesse AN

Fabricius W

Thomas CA

Abstract

Molecular profiling of urothelial cancers for therapeutic and prognostic potential has been very limited due to the absence of cancer-specific targeted therapies. We describe here 2 clinical cases with a histological diagnosis of an invasive sarcomatoid and a poorly differentiated carcinoma favoring...

Subject

Urothelial Cancer

Next-generation Sequencing

Genomic Profiling

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