Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide.

R, Karim; E, Lepeltier; L, Esnault; P, Pigeon; L, Lemaire; C, Lépinoux-Chambaud; N, Clere; G, Jaouen; J, Eyer; G, Piel; C, Passirani

doi:10.1039/c8nr02132e

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Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide.

Shared by NobleBlocks on Jul 1, 2018 • 12:00 AM UTC

Authors:

Karim R

Lepeltier E

Esnault L

Abstract

Increasing intracellular drug concentration using nanocarriers can be a potential strategy to improve efficacy against glioblastoma (GBM). Here, the fluorescent-labelled NFL-TBS·40-63 peptide (fluoNFL) concentration on a lipid nanocapsule (LNC) was studied to enhance nanovector internalization into ...

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