The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.

RJ, Commons; JA, Simpson; K, Thriemer; GS, Humphreys; T, Abreha; SG, Alemu; A, Añez; NM, Anstey; GR, Awab; JK, Baird; BE, Barber; I, Borghini-Fuhrer; CS, Chu; U, D'Alessandro; P, Dahal; A, Daher; Vries PJ, de; A, Erhart; MSM, Gomes; L, Gonzalez-Ceron; MJ, Grigg; A, Heidari; J, Hwang; PA, Kager; T, Ketema; WA, Khan; MVG, Lacerda; T, Leslie; B, Ley; K, Lidia; WM, Monteiro; F, Nosten; DB, Pereira; GT, Phan; AP, Phyo; M, Rowland; K, Saravu; CH, Sibley; AM, Siqueira; K, Stepniewska; I, Sutanto; WRJ, Taylor; G, Thwaites; BQ, Tran; HT, Tran; N, Valecha; JLF, Vieira; S, Wangchuk; T, William; CJ, Woodrow; L, Zuluaga-Idarraga; PJ, Guerin; NJ, White; RN, Price

doi:10.1016/s1473-3099(18)30348-7

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The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis.

Shared by NobleBlocks on Jul 20, 2018 • 12:00 AM UTC

Authors:

Commons RJ

Simpson JA

Thriemer K

Abstract

<h4>Background</h4>Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria despite increasing reports of treatment failure. We did a systematic review and meta-analysis to investigate the effect of chloroquine dose and the addition of primaquine on the risk of recurrent vivax mala...

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