Global DNA 5-Hydroxymethylcytosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma.

J, Liu; J, Jiang; J, Mo; D, Liu; D, Cao; H, Wang; Y, He; H, Wang

doi:10.1002/hep.30146

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Global DNA 5-Hydroxymethylcytosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma.

Shared by NobleBlocks on Dec 17, 2018 • 12:00 AM UTC

Authors:

Liu J

Jiang J

Mo J

Abstract

Methylation of the fifth position of cytosine (5mC) is an important epigenetic modification of DNA. It has been shown that the oxidized derivatives of 5mC, namely 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), are in dynamic existence and have distinct regulat...

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