Myeloid-derived suppressor cell accumulation in renal cell carcinoma is correlated with CCL2, IL-17 and IL-18 expression in blood and tumors.

X, Guan; Z, Liu; J, Zhang; X, Jin

doi:10.17219/acem/70065

Public

Myeloid-derived suppressor cell accumulation in renal cell carcinoma is correlated with CCL2, IL-17 and IL-18 expression in blood and tumors.

Shared by NobleBlocks on Jul 1, 2018 • 12:00 AM UTC

Authors:

Guan X

Liu Z

Zhang J

Abstract

<h4>Background</h4>Myeloid-derived suppressor cells (MDSC) play an important role in tumor-mediated immune evasion. Levels of MDSC in peripheral blood are increased in patients with cancer, correlating with cancer stage and outcome. Studies have confirmed the associations between MDSC and various cy...

Subject

Interleukin 17

Renal cell carcinoma

Interleukin 18

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