Environmental risk assessment of metformin and its transformation product guanylurea: II. Occurrence in surface waters of Europe and the United States and derivation of predicted no-effect concentrations.

DJ, Caldwell; V, D'Aco; T, Davidson; K, Kappler; RJ, Murray-Smith; SF, Owen; PF, Robinson; B, Simon-Hettich; JO, Straub; J, Tell

doi:10.1016/j.chemosphere.2018.10.038

Public

Environmental risk assessment of metformin and its transformation product guanylurea: II. Occurrence in surface waters of Europe and the United States and derivation of predicted no-effect concentrations.

Shared by NobleBlocks on Oct 15, 2018 • 12:00 AM UTC

Authors:

Caldwell DJ

D'Aco V

Davidson T

Abstract

Metformin (MET), CAS 1115-70-4 (Metformin hydrochloride), is an antidiabetic drug with high usage in North America and Europe and has become the subject of regulatory interest. A pharmaceutical industry working group investigated environmental risks of MET. Environmental fate and chronic effects dat...

Subject

Modeling

Metformin

Surface water

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