Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

A, Bex; P, Mulders; M, Jewett; J, Wagstaff; Thienen JV, van; CU, Blank; Velthoven R, van; Pilar Laguna M, Del; L, Wood; Melick HHE, van; MJ, Aarts; JB, Lattouf; T, Powles; Jong Md PhD IJ, de; S, Rottey; B, Tombal; S, Marreaud; S, Collette; L, Collette; J, Haanen

doi:10.1001/jamaoncol.2018.5543

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Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

Shared by NobleBlocks on Feb 1, 2019 • 12:00 AM UTC

Authors:

Bex A

Mulders P

Jewett M

Abstract

<h4>Importance</h4>In clinical practice, patients with primary metastatic renal cell carcinoma (mRCC) have been offered cytoreductive nephrectomy (CN) followed by targeted therapy, but the optimal sequence of surgery and systemic therapy is unknown.<h4>Objective</h4>To examine whether a period of su...

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