Oral versus Intravenous Antibiotics for Bone and Joint Infection

Li, Ho‐Kwong; Rombach, I.; Zambellas, R.; Walker, S.; McNally, M.; Atkins, B.; A Lipsky, Benjamin; Hughes, H.; Bose, D.; Kümin, Michelle; Scarborough, C.; Matthews, P.; Brent, A.; Lomas, J.; Gundle, R.; Rogers, M.; Taylor, Adrian; Angus, B.; Byren, I.; Berendt, A.; Warren, S.; Fitzgerald, F.; Mack, D.; Hopkins, S.; Folb, J.; Reynolds, H.; Moore, E.; Marshall, J.; Jenkins, N.; E. Moran, C.; Woodhouse, A.; Stafford, S.; Seaton, A.; Vallance, C.; Hemsley, C.; Bisnauthsing, K.; Sandoe, J.; Aggarwal, I.; Ellis, S.; Bunn, Deborah; Sutherland, R.; Barlow, G.; Cooper, C.; Geue, C.; McMeekin, N.; Briggs, A.; Sendi, P.; Khatamzas, E.; Wangrangsimakul, T.; Wong, N.; Barrett, L.; Alvand, A.; Old, Fraser; Bostock, J.; Paul, J.; Cooke, G.; Thwaites, G.; Bejon, P.; Scarborough, M.

doi:10.1056/NEJMoa1710926

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Oral versus Intravenous Antibiotics for Bone and Joint Infection

Shared by NobleBlocks on Jan 31, 2019 • 12:00 AM UTC

Authors:

Ho‐Kwong Li

I. Rombach

R. Zambellas

Abstract

BACKGROUND The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic therapy for this indication. METHODS We enrolled adults who were being treated for...

Subject

Medicine

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