Optogenetic Stimulation of the M2 Cortex Reverts Motor Dysfunction in a Mouse Model of Parkinson's Disease.

LAV, Magno; H, Tenza-Ferrer; M, Collodetti; MFG, Aguiar; APC, Rodrigues; Silva RS, da; JDP, Silva; NF, Nicolau; DVF, Rosa; A, Birbrair; DM, Miranda; MA, Romano-Silva

doi:10.1523/jneurosci.2277-18.2019

Public

Optogenetic Stimulation of the M2 Cortex Reverts Motor Dysfunction in a Mouse Model of Parkinson's Disease.

Shared by NobleBlocks on Feb 19, 2019 • 12:00 AM UTC

Authors:

Magno LAV

Tenza-Ferrer H

Collodetti M

Abstract

Neuromodulation of deep brain structures (deep brain stimulation) is the current surgical procedure for treatment of Parkinson's disease (PD). Less studied is the stimulation of cortical motor areas to treat PD symptoms, although also known to alleviate motor disturbances in PD. We were able to show...

Subject

Movement

Cognition

prefrontal cortex

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