Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective.

J, Damoiseaux; LEC, Andrade; OG, Carballo; K, Conrad; PLC, Francescantonio; MJ, Fritzler; de la Torre I, Garcia; M, Herold; W, Klotz; WM, Cruvinel; T, Mimori; Muhlen C, von; M, Satoh; EK, Chan

doi:10.1136/annrheumdis-2018-214436

Public

Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective.

Shared by NobleBlocks on Mar 12, 2019 • 12:00 AM UTC

Authors:

Damoiseaux J

Andrade LEC

Carballo OG

Abstract

The indirect immunofluorescence assay (IIFA) on HEp-2 cells is widely used for detection of antinuclear antibodies (ANA). The dichotomous outcome, negative or positive, is integrated in diagnostic and classification criteria for several systemic autoimmune diseases. However, the HEp-2 IIFA test has ...

Subject

Indirect immunofluorescence

Antinuclear Antibodies

Clinical Interpretation

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