Impact of hypertensive emergency and rare complement variants on the presentation and outcome of atypical hemolytic uremic syndrome.

Karoui K, El; I, Boudhabhay; F, Petitprez; P, Vieira-Martins; F, Fakhouri; J, Zuber; F, Aulagnon; M, Matignon; E, Rondeau; L, Mesnard; JM, Halimi; V, Frémeaux-Bacchi

doi:10.3324/haematol.2019.216903

Public

Impact of hypertensive emergency and rare complement variants on the presentation and outcome of atypical hemolytic uremic syndrome.

Shared by NobleBlocks on Mar 19, 2019 • 12:00 AM UTC

Authors:

El Karoui K

Boudhabhay I

Petitprez F

Abstract

A typical hemolytic uremic syndrome (aHUS) is a prototypic thrombotic microangiopathy attributable to complement dysregulation. Hypertensive emergency, characterized by elevation of systolic (>180 mmHg) or diastolic (>120 mmHg) blood pressure together with end-organ damage, can cause thrombotic micr...

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