Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome

Scholl, S.; Popovic, M.; de la Rochefordière, A.; Girard, E.; Dureau, S.; Mandić, A.; Koprivsek, K.; Samet, Nina; Craina, M.; Margan, Mădălin-Marius; Samuels, S.; Zijlmans, H.; Kenter, G.; Hillemanns, P.; Dema, S.; Dema, A.; Malenković, Goran; Djuran, B.; Floquet, A.; Garbay, D.; Guyon, F.; Colombo, P.; Fabbro, M.; Kerr, C.; Ngô, C.; Lécuru, F.; R. D. Campo, E.; Coutant, C.; Marchal, F.; Mesgouez-Nebout, N.; Fourchotte, V.; Féron, J.; Morice, P.; Deutsch, E.; Wimberger, P.; Classe, J.; Gleeson, N.; E. von der Leyen, H.; Minsat, M.; Dubot, C.; Gestraud, P.; Kereszt, A.; Nagy, I.; Bálint, Balázs; Berns, E.; Jordanova, E.; de Saint-Jorre, Nicolas; Savignoni, A.; Servant, N.; Hupé, P.; de Koning, L.; Fumoleau, P.; Rouzier, R.; Kamal, M.

doi:10.1016/j.ebiom.2019.03.069

Public

Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome

Shared by NobleBlocks on Apr 2, 2019 • 12:00 AM UTC

Authors:

S. Scholl

M. Popovic

A. de la Rochefordière

Abstract

Background There is a lack of information as to which molecular processes, present at diagnosis, favor tumour escape from standard-of-care treatments in cervical cancer (CC). RAIDs consortium (www.raids-fp7.eu), conducted a prospectively monitored trial, [BioRAIDs (NCT02428842)] with the objectives ...

Subject

Medicine

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