N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is identified as the most common, abundant and conserved internal transcriptional modification, especially within eukaryotic messenger RNAs (mRNAs). M<sup>6</sup>A modification is installed by the m<sup>6</sup>A methyltransferases (METTL3/14, WTAP, RBM1...