Genome-wide association study identifies 30 loci associated with bipolar disorder.

EA, Stahl; G, Breen; AJ, Forstner; A, McQuillin; S, Ripke; V, Trubetskoy; M, Mattheisen; Y, Wang; JRI, Coleman; HA, Gaspar; Leeuw CA, de; S, Steinberg; JMW, Pavlides; M, Trzaskowski; EM, Byrne; TH, Pers; PA, Holmans; AL, Richards; L, Abbott; E, Agerbo; H, Akil; D, Albani; N, Alliey-Rodriguez; TD, Als; A, Anjorin; V, Antilla; S, Awasthi; JA, Badner; M, Bækvad-Hansen; JD, Barchas; N, Bass; M, Bauer; R, Belliveau; SE, Bergen; CB, Pedersen; E, Bøen; MP, Boks; J, Boocock; M, Budde; W, Bunney; M, Burmeister; J, Bybjerg-Grauholm; W, Byerley; M, Casas; F, Cerrato; P, Cervantes; K, Chambert; AW, Charney; D, Chen; C, Churchhouse; TK, Clarke; W, Coryell; DW, Craig; C, Cruceanu; D, Curtis; PM, Czerski; AM, Dale; Jong S, de; F, Degenhardt; J, Del-Favero; JR, DePaulo; S, Djurovic; AL, Dobbyn; A, Dumont; T, Elvsåshagen; V, Escott-Price; CC, Fan; SB, Fischer; M, Flickinger; TM, Foroud; L, Forty; J, Frank; C, Fraser; NB, Freimer; L, Frisén; K, Gade; D, Gage; J, Garnham; C, Giambartolomei; MG, Pedersen; J, Goldstein; SD, Gordon; K, Gordon-Smith; EK, Green; MJ, Green; TA, Greenwood; J, Grove; W, Guan; J, Guzman-Parra; ML, Hamshere; M, Hautzinger; U, Heilbronner; S, Herms; M, Hipolito; P, Hoffmann; D, Holland; L, Huckins; S, Jamain; JS, Johnson; A, Juréus; R, Kandaswamy; R, Karlsson; JL, Kennedy; S, Kittel-Schneider; JA, Knowles; M, Kogevinas; AC, Koller; R, Kupka; C, Lavebratt; J, Lawrence; WB, Lawson; M, Leber; PH, Lee; SE, Levy; JZ, Li; C, Liu; S, Lucae; A, Maaser; DJ, MacIntyre; PB, Mahon; W, Maier; L, Martinsson; S, McCarroll; P, McGuffin; MG, McInnis; JD, McKay; H, Medeiros; SE, Medland; F, Meng; L, Milani; GW, Montgomery; DW, Morris; TW, Mühleisen; N, Mullins; H, Nguyen; CM, Nievergelt; AN, Adolfsson; EA, Nwulia; C, O'Donovan; LMO, Loohuis; APS, Ori; L, Oruc; U, Ösby; RH, Perlis; A, Perry; A, Pfennig; JB, Potash; SM, Purcell; EJ, Regeer; A, Reif; CS, Reinbold; JP, Rice; F, Rivas; M, Rivera; P, Roussos; DM, Ruderfer; E, Ryu; C, Sánchez-Mora; AF, Schatzberg; WA, Scheftner; NJ, Schork; Weickert C, Shannon; T, Shehktman; PD, Shilling; E, Sigurdsson; C, Slaney; OB, Smeland; JL, Sobell; Hansen C, Søholm; AT, Spijker; Clair D, St; M, Steffens; JS, Strauss; F, Streit; J, Strohmaier; S, Szelinger; RC, Thompson; TE, Thorgeirsson; J, Treutlein; H, Vedder; W, Wang; SJ, Watson; TW, Weickert; SH, Witt; S, Xi; W, Xu; AH, Young; P, Zandi; P, Zhang; S, Zöllner; R, Adolfsson; I, Agartz; M, Alda; L, Backlund; BT, Baune; F, Bellivier; WH, Berrettini; JM, Biernacka

doi:10.1038/s41588-019-0397-8

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Genome-wide association study identifies 30 loci associated with bipolar disorder.

Shared by NobleBlocks on May 1, 2019 • 12:00 AM UTC

Authors:

Stahl EA

Breen G

Forstner AJ

Abstract

Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P -4 in an additional 9,412 cases and 137,760 controls. Eight of the 19 varian...

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